Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.45 |
| ▸ | ALB | P02768 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.45 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | DUT | P33316 | 1/20 | 0.37 |
| ▸ | POLG | P54098 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821 | 0.87 | LMNA (0.55) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL14580321 | 0.87 | LMNA (0.55) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL1980249 | 0.87 | LMNA (0.55) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL7154210 | 0.87 | LMNA (0.55) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL8644096 | 0.83 | LMNA (0.45) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL1739891 | 0.80 | POLG (0.48) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL10510561 | 0.78 | HRAS (0.44) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL10512002 | 0.78 | DUT (0.42) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL10512094 | 0.76 | NLRP3 (0.44) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL13770316 | 0.75 | ALB (0.47) | LMNAALBDUTPOLGPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149479-A1 | SYNTHESIS OF MODIFIED NUCLEOSIDE TRIPHOSPHATES | ROCHE DIAGNOSTICS GMBH (DE) | 2025-07-17 | — | — | WO | disclosed |