Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 6/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26091520 | 0.80 | STK17B (0.51) | STK17BMAOBADORA3CYP19A1AR | |
| SCHEMBL11105016 | 0.78 | HTR2A (0.50) | STK17BMAOBADORA3CYP19A1AR | |
| SCHEMBL9147271 | 0.77 | STK17B (0.65) | STK17BMAOBADORA3CYP19A1AR | |
| SCHEMBL28022789 | 0.76 | STK17B (0.51) | STK17BMAOBADORA3CYP19A1AR | |
| SCHEMBL1429502 | 0.75 | STK17B (0.46) | STK17BMAOBADORA3CYP19A1AR | |
| SCHEMBL5695188 | 0.74 | STK17B (0.47) | STK17BMAOBARRETKDR | |
| SCHEMBL22497867 | 0.73 | STK17B (0.46) | STK17BMAOBCYP19A1KDM4ERET | |
| SCHEMBL11590452 | 0.73 | PGR (0.46) | STK17BARPARP1 | |
| SCHEMBL5548145 | 0.72 | RET (0.46) | STK17BMAOBADORA3CYP19A1AR | |
| SCHEMBL10920133 | 0.72 | ALDH1A1 (0.50) | KDM4EHSD17B10MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213006-B1 | DERIVATIVES OF 2,3-DIHYDRO-BENZOFURANE, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1989-01-25 | — | — | EP | disclosed |
| EP-0213006-A1 | Derivatives of 2,3-dihydro-benzofurane, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1987-03-04 | — | — | EP | disclosed |