Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | FASN | P49327 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8126786 | 0.77 | ABCB1 (0.53) | STK17BMAOBCYP19A1KDM4EAR | |
| SCHEMBL10513412 | 0.77 | STK17B (0.51) | STK17BMAOBPARP1CYP19A1KDM4E | |
| SCHEMBL21083145 | 0.76 | STK17B (0.64) | STK17BMAOBKDM4EKDR | |
| SCHEMBL7629569 | 0.76 | CTRB1 (0.53) | MAOBCTRB1FASNGRM2 | |
| SCHEMBL28566206 | 0.75 | LTB4R (0.45) | STK17BMAOBSIGMAR1HTR1APGR | |
| SCHEMBL8056054 | 0.74 | ALDH1A1 (0.55) | MAOBKDM4EHSD17B10CTRB1FASN | |
| SCHEMBL2858795 | 0.74 | CTRB1 (0.52) | MAOBCTRB1FASNGRM2 | |
| SCHEMBL5728556 | 0.74 | MAOB (0.53) | STK17BMAOBSIGMAR1HTR1APARP1 | |
| Fluoride SCHEMBL28653361 | 0.73 | ALDH1A1 (0.54) | MAOBKDM4EHSD17B10CTRB1 | |
| SCHEMBL5670687 | 0.73 | ALDH1A1 (0.56) | PARP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110165099-A1 | Oxidation Resistant Dentifrice Compositions | ARVANITIDOU EVANGELIA S | 2011-07-07 | — | — | US | disclosed |
| EP-1251818-B9 | GALENIC FORMULATION | MERCK PATENT GMBH (DE) | 2009-01-07 | — | — | EP | disclosed |
| EP-1251818-B1 | GALENIC FORMULATION | MERCK PATENT GMBH (DE) | 2008-07-02 | — | — | EP | disclosed |
| US-5459139-A | Antitumor agents, anticholesterol agents, antiestrogens, treatment of breast cancer | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 1995-10-17 | — | — | US | disclosed |
| US-5354861-A | Binds to antiestrogen binding sites; antiproliferative activity | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 1994-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165099-A1 | Oxidation Resistant Dentifrice Compositions | DNMT1, DNMT3A, CAT | STK17B 3787/4885MAOB 3569/4885SIGMAR1 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.