Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10511566 | 0.94 | MAPT (0.47) | MAPTRXFP1HTTKMT2AALDH1A1 | |
| SCHEMBL10511756 | 0.76 | RAB9A (0.47) | MAPTRXFP1HTTKMT2AALDH1A1 | |
| SCHEMBL10510883 | 0.76 | KDM4E (0.51) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL10483334 | 0.75 | KDM4E (0.68) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL10513759 | 0.69 | MAPT (0.51) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL14760445 | 0.68 | KDM4E (0.72) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL10512800 | 0.68 | KDM4E (0.71) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL7638112 | 0.68 | MAPT (0.66) | MAPTRXFP1HTTKMT2AMEN1 | |
| SCHEMBL28574640 | 0.67 | KDM4E (0.78) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL7745218 | 0.65 | MAPT (0.52) | MAPTRXFP1HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331093-A1 | Benzimidazo[1,2-c]quinazolines, their preparation and use | KNOLL AG (DE) | 1989-09-06 | — | — | EP | disclosed |