Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745481 | 0.77 | CNR2 (0.50) | MAPTKMT2AMEN1LMNACNR1 | |
| SCHEMBL7745480 | 0.74 | TOP2A (0.47) | MAPTKMT2AMEN1LMNAOPRM1 | |
| SCHEMBL7740578 | 0.73 | TOP2A (0.46) | MAPTHTTKMT2AMEN1LMNA | |
| SCHEMBL7745467 | 0.73 | TOP2A (0.49) | MAPTKMT2AMEN1LMNAOPRM1 | |
| SCHEMBL7638112 | 0.73 | MAPT (0.66) | MAPTRXFP1HTTIRAK4KMT2A | |
| SCHEMBL11833660 | 0.73 | MAPT (0.70) | MAPTRXFP1HTTKMT2AMEN1 | |
| SCHEMBL7745483 | 0.73 | MAPT (0.47) | MAPTKMT2AMEN1LMNACNR1 | |
| SCHEMBL26630273 | 0.71 | MAPT (0.51) | MAPTKMT2AMEN1LMNACNR1 | |
| SCHEMBL7746704 | 0.70 | TOP2A (0.55) | MAPTRXFP1HTTKMT2AMEN1 | |
| SCHEMBL24900462 | 0.70 | MAPT (0.55) | MAPTRXFP1HTTIRAK4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |