Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10512619 | 0.91 | MAT2A (0.48) | MAT2AFLT3KDM4EHSP90AA1MAPK1 | |
| SCHEMBL10511601 | 0.88 | POLB (0.47) | KDM4EHSP90AA1MAPK1MCL1KMT2A | |
| SCHEMBL10513493 | 0.87 | KDM4E (0.52) | KDM4EHSP90AA1MAPK1MCL1KMT2A | |
| SCHEMBL10513759 | 0.81 | MAPT (0.51) | MAT2AFLT3KDM4EKMT2AALDH1A1 | |
| SCHEMBL10514017 | 0.72 | HPGD (0.47) | KDM4EKMT2AALDH1A1MEN1POLB | |
| SCHEMBL10510883 | 0.72 | KDM4E (0.51) | MAT2AKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL21208568 | 0.71 | IKBKB (0.47) | MAT2AKDM4EHSP90AA1MAPK1MCL1 | |
| SCHEMBL28064513 | 0.70 | HDAC1 (0.65) | MAT2AKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL21208490 | 0.68 | KMT2A (0.48) | KDM4EHSP90AA1MAPK1MCL1KMT2A | |
| SCHEMBL20821410 | 0.67 | KDM4E (0.55) | KDM4EKMT2AALDH1A1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331093-A1 | Benzimidazo[1,2-c]quinazolines, their preparation and use | KNOLL AG (DE) | 1989-09-06 | — | — | EP | disclosed |