Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668836 | 0.74 | BRD4 (0.38) | BRD4TDP1HSP90AA1TDP2NSD2 | |
| Hydrochloric Acid SCHEMBL27167119 | 0.72 | BRD4 (0.37) | BRD4TDP1HSP90AA1TDP2NSD2 | |
| Hydrochloric Acid SCHEMBL27167121 | 0.72 | BRD4 (0.37) | BRD4TDP1HSP90AA1TDP2NSD2 | |
| SCHEMBL27713894 | 0.72 | BRD4 (0.37) | BRD4TDP1HSP90AA1TDP2NSD2 | |
| SCHEMBL670066 | 0.71 | BRD4 (0.36) | BRD4TDP1TDP2NSD2ABL1 | |
| SCHEMBL27414230 | 0.69 | BRD4 (0.35) | BRD4NOS3NOS1NOS2 | |
| SCHEMBL4640929 | 0.65 | HTT (0.33) | TDP1HSP90AA1TDP2NSD2ABL1 | |
| SCHEMBL4646997 | 0.62 | HTT (0.34) | TDP1HSP90AA1KDM4EMAPTGMNN | |
| SCHEMBL1665761 | 0.61 | TDP2 (0.32) | BRD4TDP1TDP2NSD2ABL1 | |
| SCHEMBL1712089 | 0.61 | TDP2 (0.32) | BRD4TDP1TDP2NSD2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347698-A1 | Heterobicyclic compounds having antiinflammatory activity | SCHERING CORPORATION (US) | 1989-12-27 | — | — | EP | claimed |