SCHEMBL10514152

SCHEMBL10514152

O=C1CCC(=O)N1CCN1CCN(c2cccc3ccoc23)CC1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.56
DRD2 P14416 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10513397 0.84 ADRA1B (0.63)
Hydrochloric Acid SCHEMBL10513723 0.83 ADRA1B (0.62)
SCHEMBL10514665 0.81
SCHEMBL10515450 0.80
SCHEMBL10524008 0.80
SCHEMBL10513645 0.78
SCHEMBL10514687 0.78
SCHEMBL10516639 0.77 HTR1A (0.68) HTR1ADRD2
SCHEMBL13533025 0.76 HTR1A (0.83) HTR1ADRD2
SCHEMBL10514753 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0190472-B1 NEW PHARMACEUTICAL COMPOSITIONS HAVING ANTI-PSYCHOTIC PROPERTIES DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1989-07-12 EP claimed
EP-0190472-A1 New pharmaceutical compositions having anti-psychotic properties DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1986-08-13 EP claimed
EP-0190472-B1 NEW PHARMACEUTICAL COMPOSITIONS HAVING ANTI-PSYCHOTIC PROPERTIES DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1989-07-12 EP disclosed
US-4782061-A CENTRAL NERVOUS SYSTEM DISORDERS DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1988-11-01 US disclosed
EP-0190472-A1 New pharmaceutical compositions having anti-psychotic properties DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1986-08-13 EP disclosed