Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 3/20 | 0.63 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10513723 | 0.99 | ADRA1B (0.62) | ADRA1BADRA1DADRA1A | |
| SCHEMBL10514152 | 0.84 | HTR1A (0.56) | — | |
| SCHEMBL9306135 | 0.81 | ADRA1D (0.66) | ADRA1BADRA1DADRA1A | |
| SCHEMBL10514665 | 0.79 | — | — | |
| SCHEMBL8142907 | 0.78 | DRD2 (0.55) | — | |
| SCHEMBL10524008 | 0.77 | — | — | |
| SCHEMBL10515450 | 0.77 | — | — | |
| SCHEMBL10513645 | 0.75 | — | — | |
| SCHEMBL10514687 | 0.75 | — | — | |
| SCHEMBL10519236 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0190472-B1 | NEW PHARMACEUTICAL COMPOSITIONS HAVING ANTI-PSYCHOTIC PROPERTIES | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1989-07-12 | — | — | EP | claimed |
| EP-0190472-A1 | New pharmaceutical compositions having anti-psychotic properties | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1986-08-13 | — | — | EP | claimed |
| EP-0190472-B1 | NEW PHARMACEUTICAL COMPOSITIONS HAVING ANTI-PSYCHOTIC PROPERTIES | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1989-07-12 | — | — | EP | disclosed |
| US-4782061-A | CENTRAL NERVOUS SYSTEM DISORDERS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1988-11-01 | — | — | US | disclosed |
| EP-0190472-A1 | New pharmaceutical compositions having anti-psychotic properties | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1986-08-13 | — | — | EP | disclosed |