Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 16/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 15/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | FPR3 | P25089 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10338191 | 0.84 | ADRB2 (0.52) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL10513963 | 0.84 | ADRB2 (0.49) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL9864677 | 0.82 | ADRB2 (0.67) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL461364 | 0.82 | ADRB2 (0.70) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL29751132 | 0.82 | ADRB2 (0.70) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL10514014 | 0.80 | ADRB2 (0.52) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL10697205 | 0.78 | ADRB2 (0.64) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL10701369 | 0.78 | ADRB2 (0.53) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL9509489 | 0.76 | SLC2A1 (0.48) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL10513973 | 0.76 | ADRB2 (0.52) | ADRB2ADRB1ADRB3KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322164-A2 | Ethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1989-06-28 | — | — | EP | claimed |