Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TYMS | P04818 | 5/20 | 0.44 |
| ▸ | DHFR | P00374 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.39 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10522672 | 0.87 | MAPT (0.54) | ALDH1A1KDM4ETDP1MAPTMEN1 | |
| SCHEMBL10516611 | 0.82 | MAPT (0.53) | ALDH1A1KDM4ETDP1MAPTMEN1 | |
| SCHEMBL10516456 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KDM4ETDP1MAPTMEN1 | |
| SCHEMBL10516058 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KDM4ETDP1MAPTMEN1 | |
| SCHEMBL10518031 | 0.80 | CYP3A4 (0.41) | KDM4EMAPTMEN1KMT2ADHFR | |
| SCHEMBL10519474 | 0.79 | DHFR (0.52) | ALDH1A1KDM4ETDP1MAPTMEN1 | |
| SCHEMBL10521296 | 0.79 | MAPT (0.51) | ALDH1A1KDM4ETDP1MAPTMEN1 | |
| SCHEMBL10522322 | 0.76 | MAPT (0.66) | ALDH1A1KDM4ETDP1MAPTMEN1 | |
| SCHEMBL10515414 | 0.76 | MAPT (0.54) | ALDH1A1KDM4ETDP1MAPTMEN1 | |
| SCHEMBL10521999 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KDM4ETDP1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302311-A2 | Aryloxy (or thio)aminopyrimidines | BAYER AG (DE) | 1989-02-08 | — | — | EP | disclosed |