Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516861 | 0.86 | CYP11B2 (0.34) | CYP11B2LMNATP53TSHRALDH1A1 | |
| SCHEMBL10387607 | 0.83 | DAPK3 (0.36) | CYP11B2LMNATP53TSHRALDH1A1 | |
| SCHEMBL9531257 | 0.75 | CYP11B2 (0.33) | CYP11B2LMNATP53TSHRALDH1A1 | |
| SCHEMBL9535378 | 0.74 | CYP11B2 (0.34) | CYP11B2LMNATSHRALDH1A1 | |
| SCHEMBL10515921 | 0.72 | IDO1 (0.34) | CYP11B2 | |
| SCHEMBL10387985 | 0.71 | CYP11B2 (0.45) | CYP11B2TSHRALDH1A1 | |
| SCHEMBL9804859 | 0.68 | CYP11B2 (0.35) | CYP11B2LMNATP53TSHRALDH1A1 | |
| SCHEMBL10389944 | 0.67 | DAPK3 (0.37) | CYP11B2LMNATP53TSHRALDH1A1 | |
| SCHEMBL10390416 | 0.66 | DAPK3 (0.36) | CYP11B2LMNATP53TSHRALDH1A1 | |
| SCHEMBL10699956 | 0.62 | CYP11B2 (0.36) | CYP11B2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305332-A2 | Imidazole derivative | CIBA-GEIGY AG (CH) | 1989-03-01 | — | — | EP | disclosed |