Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.79 |
| ▸ | RAB9A | P51151 | 3/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.79 |
| ▸ | NPC1 | O15118 | 2/20 | 0.79 |
| ▸ | PDE4A | P27815 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10517136 | 0.82 | ALDH1A1 (0.64) | ALDH1A1KDM4EMAPK1HSD17B10RAB9A | |
| SCHEMBL11264274 | 0.77 | PDE4A (0.69) | ALDH1A1KDM4EMAPK1HSD17B10RAB9A | |
| SCHEMBL10517126 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPK1HSD17B10RAB9A | |
| SCHEMBL8536799 | 0.75 | NPC1 (0.58) | ALDH1A1KDM4EMAPK1HSD17B10RAB9A | |
| SCHEMBL10518453 | 0.75 | NPC1 (0.54) | ALDH1A1KDM4EMAPK1HSD17B10RAB9A | |
| SCHEMBL4117707 | 0.75 | NPC1 (0.77) | ALDH1A1KDM4EMAPK1HSD17B10RAB9A | |
| SCHEMBL9834670 | 0.74 | ALDH1A1 (0.59) | ALDH1A1KDM4EMAPK1HSD17B10RAB9A | |
| SCHEMBL28025164 | 0.73 | NPC1 (0.51) | ALDH1A1KDM4EMAPK1HSD17B10RAB9A | |
| SCHEMBL3125629 | 0.73 | PDE4A (0.72) | ALDH1A1KDM4EMAPK1HSD17B10RAB9A | |
| SCHEMBL28025701 | 0.73 | NPC1 (0.46) | ALDH1A1KDM4EMAPK1HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104910105-A | Method for preparation of polysubstituted furan derivative from gem-difluoroolefin | UNIV EAST CHINA SCIENCE & TECH | 2015-09-16 | — | — | CN | disclosed |