Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 8/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 7/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.39 |
| ▸ | PDE4A | P27815 | 6/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9559266 | 0.98 | ATAD2 (0.44) | ATAD2PDK2PDK4PGRMAPK14 | |
| SCHEMBL4138321 | 0.85 | ATAD2 (0.50) | ATAD2PDK2PDK4PGRMAPK14 | |
| SCHEMBL5757053 | 0.80 | ATAD2 (0.46) | ATAD2PDK2PDK4PGRMAPK14 | |
| SCHEMBL31219713 | 0.79 | ATAD2 (0.45) | ATAD2PDK2PDK4PGRMAPK14 | |
| SCHEMBL2490212 | 0.76 | PDK2 (0.45) | ATAD2PDK2PDK4PGRMAPK14 | |
| SCHEMBL31335591 | 0.76 | ATAD2 (0.42) | ATAD2PDK2PDK4PGRMAPK14 | |
| SCHEMBL31335589 | 0.76 | ATAD2 (0.42) | ATAD2PDK2PDK4PGRMAPK14 | |
| SCHEMBL2487418 | 0.73 | TDP1 (0.49) | ATAD2PDK2PDK4PGRPDE3B | |
| SCHEMBL9559318 | 0.73 | PGR (0.48) | ATAD2PDK2PDK4PGRPDE3B | |
| SCHEMBL2486621 | 0.72 | PDK2 (0.45) | ATAD2PDK2PDK4PGRMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0334289-A1 | Heterocyclic substituted 5,7-dihydropyrrolo (3,2-f) benzoxazol-6-ones, process for their preparation and drugs containing same | Roche Diagnostics GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |