Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 7/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335589 | 1.00 | ATAD2 (0.42) | ATAD2PDK2PDK4PGRMAPK14 | |
| SCHEMBL30035471 | 0.82 | ATAD2 (0.41) | ATAD2PDK2PDK4PGRMAPK14 | |
| SCHEMBL30459958 | 0.82 | PGR (0.43) | ATAD2PDK2PDK4PGRMAPK14 | |
| SCHEMBL23577902 | 0.82 | ATAD2 (0.41) | ATAD2PDK2PDK4PGRMAPK14 | |
| SCHEMBL25156363 | 0.80 | MAPK14 (0.46) | ATAD2PDK2PDK4PGRMAPK14 | |
| SCHEMBL31335972 | 0.80 | ALDH1A1 (0.44) | ATAD2PDK2PDK4PGRMAPK14 | |
| SCHEMBL5757053 | 0.77 | ATAD2 (0.46) | ATAD2PDK2PDK4PGRMAPK14 | |
| SCHEMBL10517587 | 0.76 | ATAD2 (0.45) | ATAD2PDK2PDK4PGRMAPK14 | |
| Hydrochloric Acid SCHEMBL9559266 | 0.75 | ATAD2 (0.44) | ATAD2PDK2PDK4PGRMAPK14 | |
| SCHEMBL31335946 | 0.72 | RXRA (0.42) | PGRRXRACSNK2A1RARBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |