Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | ESRRB | O95718 | 1/20 | 0.45 |
| ▸ | ESRRA | P11474 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10517623 | 0.86 | PDGFRB (0.51) | PDGFRBPDGFRAESR1ESR2KDM1A | |
| SCHEMBL10519151 | 0.78 | KDM1A (0.41) | ESR1ESR2ESRRBESRRAKDM1A | |
| SCHEMBL10517064 | 0.76 | ESR1 (0.57) | ESR1ESR2ESRRBESRRAKDM4E | |
| SCHEMBL10519275 | 0.76 | ESR1 (0.50) | ESR1ESR2ESRRBESRRAKDM1A | |
| SCHEMBL10337641 | 0.72 | KDM1A (0.47) | KDM1AKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL1338049 | 0.71 | PDGFRB (0.51) | PDGFRBPDGFRAKDM1ASLC2A1EGFR | |
| SCHEMBL14696946 | 0.70 | LMNA (0.75) | PDGFRBPDGFRAESR1ESR2KDM1A | |
| SCHEMBL26075531 | 0.68 | MAPT (0.60) | ESR1ESR2ESRRBESRRAKDM4E | |
| SCHEMBL12151481 | 0.66 | APP (0.46) | MAPTSMN1; SMN2SYK | |
| SCHEMBL8366935 | 0.66 | PDE3B (0.49) | KDM4EMAPTALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339518-A2 | Quinoline compounds and their use | BASF Aktiengesellschaft (DE) | 1989-11-02 | — | — | EP | disclosed |