Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 8/20 | 0.40 |
| ▸ | ESRRB | O95718 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 4/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10337641 | 0.82 | KDM1A (0.47) | KDM1ASYKAPPCYP3A4KDM4E | |
| SCHEMBL10518948 | 0.78 | PDGFRB (0.46) | KDM1ASYKESRRBESR1ESRRA | |
| SCHEMBL10519275 | 0.77 | ESR1 (0.50) | KDM1ASYKESRRBESR1ESRRA | |
| SCHEMBL10517064 | 0.72 | ESR1 (0.57) | SYKESRRBESR1ESRRAESR2 | |
| SCHEMBL10517623 | 0.69 | PDGFRB (0.51) | KDM1ASYKESR1ESR2APP | |
| SCHEMBL10682375 | 0.67 | MAPK14 (0.53) | KDM1AAPPKDM4ENPC1ALDH1A1 | |
| SCHEMBL12151481 | 0.66 | APP (0.46) | SYKAPPADKMAPTSMN1; SMN2 | |
| SCHEMBL4442718 | 0.65 | CTSK (0.70) | — | |
| SCHEMBL26074092 | 0.65 | APP (0.49) | KDM1ASYKAPPCYP3A4MEN1 | |
| SCHEMBL8618775 | 0.64 | MAPT (0.54) | SYKAPPADKKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339518-A2 | Quinoline compounds and their use | BASF Aktiengesellschaft (DE) | 1989-11-02 | — | — | EP | disclosed |