Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10521013 | 0.92 | HRH2 (0.48) | HRH2HRH3ROCK1PRKACAMEN1 | |
| SCHEMBL10518550 | 0.83 | TSHR (0.56) | HRH2MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL10519858 | 0.83 | TSHR (0.43) | ROCK1PRKACAMEN1ALDH1A1MAPT | |
| Oxalic Acid SCHEMBL10622034 | 0.79 | ALDH1A1 (0.46) | HRH2HRH3ROCK1PRKACAMEN1 | |
| SCHEMBL10623949 | 0.78 | HRH2 (0.47) | HRH2HRH3ROCK1PRKACAMEN1 | |
| SCHEMBL10870130 | 0.77 | HRH2 (0.40) | HRH2HRH3ROCK1PRKACAMEN1 | |
| SCHEMBL10518226 | 0.74 | KMT2A (0.54) | HRH2MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL10518279 | 0.74 | EHMT2 (0.44) | HRH3ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL10518291 | 0.72 | ALDH1A1 (0.45) | HRH2ROCK1MEN1ALDH1A1LMNA | |
| SCHEMBL10520446 | 0.72 | ALDH1A1 (0.42) | HRH2MEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183191-B1 | THIENYLTHIAZOLE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-10 | — | — | EP | disclosed |
| US-4720493-A | Thienylthiazole compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0183191-A1 | Thienylthiazole compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-06-04 | — | — | EP | disclosed |