Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10868918 | 0.82 | NOS1 (0.41) | MEN1LMNAMAPTKMT2AROCK1 | |
| SCHEMBL10521013 | 0.81 | HRH2 (0.48) | HRH2HRH3SMN1; SMN2MEN1GMNN | |
| SCHEMBL10519080 | 0.77 | HRH2 (0.47) | HRH2HRH3SMN1; SMN2MEN1GMNN | |
| Oxalic Acid SCHEMBL10622034 | 0.76 | ALDH1A1 (0.46) | HRH2HRH3SMN1; SMN2MEN1GMNN | |
| SCHEMBL10623949 | 0.74 | HRH2 (0.47) | HRH2HRH3SMN1; SMN2MEN1GMNN | |
| SCHEMBL13574528 | 0.71 | HRH2 (0.56) | HRH2HRH3CYP2D6HIF1A | |
| SCHEMBL10518279 | 0.70 | EHMT2 (0.44) | HRH3SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL13293358 | 0.69 | ITGB3 (0.61) | HRH2HRH3CYP2D6HIF1A | |
| SCHEMBL10871169 | 0.69 | KDM4B (0.34) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL28508095 | 0.67 | PRMT5 (0.53) | HRH3CYP2D6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183191-A1 | Thienylthiazole compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-06-04 | — | — | EP | disclosed |