Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 10/20 | 0.38 |
| ▸ | NQO1 | P15559 | 8/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10517310 | 0.94 | NQO2 (0.37) | NQO2NQO1IDO1TOP2AMITF | |
| SCHEMBL9023868 | 0.92 | NQO2 (0.38) | NQO2NQO1IDO1TOP2AGRIN1 | |
| SCHEMBL9023814 | 0.88 | NQO2 (0.36) | NQO2NQO1IDO1TOP2AMITF | |
| SCHEMBL9024437 | 0.86 | NQO2 (0.37) | NQO2NQO1IDO1MITF | |
| SCHEMBL9024127 | 0.85 | TOP2A (0.40) | NQO2NQO1TOP2A | |
| SCHEMBL9025443 | 0.83 | NQO2 (0.37) | NQO2NQO1IDO1TOP2A | |
| SCHEMBL9023796 | 0.82 | NQO2 (0.47) | NQO2NQO1MITF | |
| SCHEMBL9024018 | 0.81 | NQO2 (0.38) | NQO2NQO1IDO1TOP2AMITF | |
| SCHEMBL9023958 | 0.81 | TOP2A (0.42) | NQO2NQO1TOP2AMITF | |
| SCHEMBL9036810 | 0.78 | NQO2 (0.36) | NQO2NQO1IDO1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-A2 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-27 | — | — | EP | claimed |