Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 14/20 | 0.47 |
| ▸ | NQO1 | P15559 | 7/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023931 | 0.93 | NQO2 (0.47) | NQO2NQO1MITFSMARCA2KEAP1 | |
| SCHEMBL9024803 | 0.90 | NQO2 (0.41) | NQO2NQO1MITFSMARCA2KEAP1 | |
| SCHEMBL9023868 | 0.88 | NQO2 (0.38) | NQO2NQO1MITFSMARCA2NSD2 | |
| SCHEMBL9024639 | 0.88 | NQO2 (0.42) | NQO2NQO1MITFSMARCA2KEAP1 | |
| SCHEMBL9739746 | 0.87 | NQO2 (0.59) | NQO2NQO1MITF | |
| SCHEMBL9024437 | 0.86 | NQO2 (0.37) | NQO2NQO1MITF | |
| SCHEMBL9023958 | 0.85 | TOP2A (0.42) | NQO2NQO1MITFNSD2SMN1; SMN2 | |
| SCHEMBL9023814 | 0.84 | NQO2 (0.36) | NQO2NQO1MITF | |
| SCHEMBL9024018 | 0.84 | NQO2 (0.38) | NQO2NQO1MITFNSD2SMN1; SMN2 | |
| SCHEMBL9024127 | 0.83 | TOP2A (0.40) | NQO2NQO1NSD2SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |