Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.63 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.53 |
| ▸ | FNTA | P49354 | 2/20 | 0.44 |
| ▸ | FNTB | P49356 | 2/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6329432 | 0.92 | PTGS1 (0.55) | PTGS1GSTK1FOLH1FNTAFNTB | |
| SCHEMBL30161596 | 0.90 | PTGS1 (0.55) | PTGS1GSTK1FOLH1FNTAFNTB | |
| SCHEMBL30292792 | 0.90 | PTGS1 (0.52) | PTGS1GSTK1FOLH1GLO1GRM8 | |
| SCHEMBL30132411 | 0.89 | PTGS1 (0.56) | PTGS1GSTK1FOLH1FNTAFNTB | |
| SCHEMBL30320239 | 0.87 | PTGS1 (0.50) | PTGS1GSTK1FOLH1GLO1GRM8 | |
| SCHEMBL22111140 | 0.87 | PTGS1 (0.53) | PTGS1GSTK1FOLH1GLO1GRM8 | |
| SCHEMBL14774754 | 0.87 | PTGS1 (0.50) | PTGS1GSTK1FOLH1FNTAFNTB | |
| SCHEMBL1493227 | 0.86 | PTGS1 (0.55) | PTGS1GSTK1FOLH1FNTAFNTB | |
| SCHEMBL22589611 | 0.86 | PTGS1 (0.60) | PTGS1GSTK1FOLH1FNTAFNTB | |
| SCHEMBL22589613 | 0.86 | PTGS1 (0.60) | PTGS1GSTK1FOLH1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871528-A | REDUCED GLUTATHIONE AND CISPLATIN; SYNERGISTIC | BOEHRINGER BIOCHEMIA ROBIN SPA (IT) | 1989-10-03 | — | — | US | disclosed |