Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.55 |
| ▸ | FNTA | P49354 | 12/20 | 0.49 |
| ▸ | FNTB | P49356 | 12/20 | 0.49 |
| ▸ | PGGT1B | P53609 | 8/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30644299 | 0.90 | PTGS1 (0.52) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL29379571 | 0.88 | PTGS1 (0.47) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL30390675 | 0.88 | PTGS1 (0.50) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL21153033 | 0.87 | PTGS1 (0.48) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL10520197 | 0.86 | PTGS1 (0.63) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL29815598 | 0.86 | PTGS1 (0.49) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL30132411 | 0.86 | PTGS1 (0.56) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL29373113 | 0.85 | ACE (0.53) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL29516761 | 0.85 | ACE (0.53) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL30957279 | 0.84 | PTGS1 (0.50) | PTGS1GSTK1FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120507525-A | Plasma metabolism marker combination for predicting human aging and application thereof | 中国科学技术大学 | 2025-08-19 | — | — | CN | disclosed |
| WO-2025038670-A1 | BICYCLIC MIMICS-RIGID, CELL PERMEABLE, SERUM STABLE HELICAL MIMICS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2025-02-20 | — | — | WO | disclosed |
| WO-2024050400-A1 | METHODS OF IDENTIFYING NOX2 INHIBITORS | GENENTECH, INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| WO-2018154517-A1 | IMMUNOCYTOKINE COMBINATION THERAPY | PHILOGEN SPA (IT) | 2018-08-30 | — | — | WO | disclosed |
| US-8491906-B2 | Selective targeting of tumor vasculature using antibody molecules | PHILOGEN S.P.A. (IT) | 2013-07-23 | — | — | US | disclosed |
| EP-1663320-B1 | TARGETING OF TUMOR VASCULATURE USING RADIOLABELLED ANTIBODY L19 AGAINST FIBRONECTIN ED-B | PHILOGEN SPA (IT) | 2011-03-02 | — | — | EP | disclosed |
| EP-2246070-A2 | Targeting of tumor vasculature using radiolabelled antibody l19 against fibronectin ed-b | Philogen S.p.A. (IT) | 2010-11-03 | — | — | EP | disclosed |
| EP-2174958-A1 | Antibodies derived from anti ed-b l19 and targeting tumor vasculature | Philogen S.p.A. (IT) | 2010-04-14 | — | — | EP | disclosed |
| EP-1483297-B1 | ANTIBODIES DERIVED FROM ANTI ED-B L19 AND TARGETING TUMOR VASCULATURE | PHILOGEN SPA (IT) | 2009-12-23 | — | — | EP | disclosed |
| CN-100535013-C | Selective targeting of tumor vasculature using antibody molecules | PHILOGEN S R L SCHERING AG (IT) | 2009-09-02 | — | — | CN | disclosed |
| CN-1849144-A | Targeting of tumor vasculature using radiolabelled antibody l19 against fibronectin ED-B | PHILOGEN SPA (IT) | 2006-10-18 | — | — | CN | disclosed |
| EP-1663320-A1 | TARGETING OF TUMOR VASCULATURE USING RADIOLABELLED ANTIBODY L19 AGAINST FIBRONECTIN ED-B | Philogen S.p.A. (IT) | 2006-06-07 | — | — | EP | disclosed |
| US-20060057146-A1 | Selective targeting of tumor vasculature using antibody molecules | PHILOGEN (IT) | 2006-03-16 | — | — | US | disclosed |
| WO-2003076469-A9 | ANTIBODIES DERIVED ROM ANTI ED-B L19 AND TARGETING TUMOR VASCULATURE | PHILOGEN SPA (IT) | 2005-09-29 | — | — | WO | disclosed |
| CN-1639195-A | Selective targeting of tumor vasculature using antibody molecules | PHILOGEN SRL (IT) | 2005-07-13 | — | — | CN | disclosed |
| US-20050074401-A1 | Selective targeting of tumor vasculature using radiolabelled antibody molecules | SCHERING AG (DE) | 2005-04-07 | — | — | US | disclosed |
| WO-2005023318-A1 | TARGETING OF TUMOR VASCULATURE USING RADIOLABELLED ANTIBODY L19 AGAINST FIBRONECTIN ED-B | PHILOGEN S.P.A (IT) | 2005-03-17 | — | — | WO | disclosed |
| EP-1514561-A1 | Targeting of tumor vasculature using radiolabelled antibody L19 against fibronectin ED-B | Philogen S.p.A. (IT) | 2005-03-16 | — | — | EP | disclosed |
| EP-1483297-A2 | ANTIBODIES DERIVED FROM ANTI ED-B L19 AND TARGETING TUMOR VASCULATURE | Philogen S.p.A. (IT) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003076469-A2 | ANTIBODIES DERIVED ROM ANTI ED-B L19 AND TARGETING TUMOR VASCULATURE | PHILOGEN S.P.A. (IT) | 2003-09-18 | — | — | WO | disclosed |