Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ESRRG | P62508 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598218 | 0.86 | HIF1A (0.85) | HIF1AMAPTTRPV1LMNAL3MBTL1 | |
| SCHEMBL11258591 | 0.81 | HIF1A (0.76) | HIF1AMAPTTRPV1LMNAPOLB | |
| SCHEMBL8160653 | 0.79 | HIF1A (1.00) | HIF1AMAPTTRPV1LMNAL3MBTL1 | |
| SCHEMBL18503580 | 0.79 | HIF1A (0.60) | HIF1AMAPTTRPV1LMNAPOLB | |
| SCHEMBL5488029 | 0.78 | LMNA (0.54) | HIF1AMAPTLMNAPOLBNPC1 | |
| SCHEMBL15676770 | 0.76 | HIF1A (0.60) | HIF1AMAPTTRPV1LMNANPC1 | |
| SCHEMBL11251889 | 0.75 | SNCA (0.60) | HIF1AMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL1568227 | 0.75 | HIF1A (0.72) | HIF1AMAPTTRPV1RAB9ASMN1; SMN2 | |
| SCHEMBL1813320 | 0.75 | RAB9A (0.60) | HIF1ALMNAPOLBNPC1RAB9A | |
| SCHEMBL3639491 | 0.75 | HIF1A (0.75) | HIF1AMAPTTRPV1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340709-A1 | (3-Chloro-methyl phenyl)ethyl amines, processes for their production and their use | BASF Aktiengesellschaft (DE) | 1989-11-08 | — | — | EP | disclosed |