Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10522808 | 0.88 | KCNH2 (0.38) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2782902 | 0.87 | ALDH1A1 (0.42) | NPC1ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL105809 | 0.82 | NPC1 (0.41) | NPC1SMN1; SMN2ADRA2AADRA2BADRA2C | |
| SCHEMBL20410845 | 0.79 | NPC1 (0.39) | NPC1SMN1; SMN2 | |
| SCHEMBL28294938 | 0.79 | ALDH1A1 (0.34) | ALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL1338547 | 0.78 | NISCH (0.50) | NPC1ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL9319820 | 0.78 | SMN1; SMN2 (0.42) | NPC1ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL4465857 | 0.77 | ALDH1A1 (0.40) | ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL12284463 | 0.77 | NPC1 (0.50) | NPC1 | |
| SCHEMBL10520530 | 0.76 | KCNH2 (0.38) | NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4841002-A | Liquid aromatic bisoxazoline and disoxazine monomer mixtures cured with polyphenolic compounds | ASHLAND OIL, INC (US) | 1989-06-20 | — | — | US | disclosed |
| US-4806267-A | Liquid aromatic bisoxazoline and bisoxazine monomer mixtures and process for crosslinking using phenolics | ASHLAND OIL, INC. (US) | 1989-02-21 | — | — | US | disclosed |