Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10520201 | 0.88 | NPC1 (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2783537 | 0.86 | ALDH1A1 (0.43) | ALDH1A1HPGDNOS3NOS1NOS2 | |
| SCHEMBL28294938 | 0.84 | ALDH1A1 (0.34) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL132013 | 0.80 | KCNH2 (0.49) | KCNH2HRH3LTA4HLSSSMN1; SMN2 | |
| SCHEMBL9667808 | 0.77 | ALDH1A1 (0.38) | ALDH1A1HPGDNOS3NOS1NOS2 | |
| SCHEMBL1338840 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HPGDNOS3NOS1NOS2 | |
| SCHEMBL13934519 | 0.75 | MEN1 (0.45) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9322292 | 0.74 | ALDH1A1 (0.47) | ALDH1A1HPGDNOS3NOS1NOS2 | |
| SCHEMBL1814199 | 0.74 | KCNH2 (0.43) | KCNH2HRH3ALDH1A1HPGDLTA4H | |
| SCHEMBL4465857 | 0.74 | ALDH1A1 (0.40) | ALDH1A1NOS3NOS1NOS2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4841002-A | Liquid aromatic bisoxazoline and disoxazine monomer mixtures cured with polyphenolic compounds | ASHLAND OIL, INC (US) | 1989-06-20 | — | — | US | disclosed |
| US-4806267-A | Liquid aromatic bisoxazoline and bisoxazine monomer mixtures and process for crosslinking using phenolics | ASHLAND OIL, INC. (US) | 1989-02-21 | — | — | US | disclosed |