Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RRM1 | P23921 | 1/20 | 0.41 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10422914 | 1.00 | EPHX2 (0.48) | EPHX2TSHRLMNAALDH1A1RRM1 | |
| SCHEMBL15623812 | 0.85 | ALDH1A2 (0.54) | ALDH1A1RRM1ALDH1A2ALDH2ALDH1A3 | |
| SCHEMBL17885891 | 0.84 | TSHR (0.52) | EPHX2TSHRLMNAALDH1A1ALDH1A2 | |
| SCHEMBL18768870 | 0.83 | TSHR (0.52) | EPHX2TSHRLMNAALDH1A1ALDH1A2 | |
| SCHEMBL8390709 | 0.82 | ADRA1A (0.58) | EPHX2TSHRLMNAALDH1A1TLR2 | |
| SCHEMBL14854351 | 0.82 | TLR2 (0.48) | EPHX2LMNAALDH1A1RRM1DPP7 | |
| SCHEMBL8388348 | 0.80 | ADRA1A (0.55) | EPHX2LMNADPP7TLR2 | |
| SCHEMBL18807860 | 0.80 | DPP7 (0.50) | EPHX2RRM1DPP7TLR2S1PR2 | |
| SCHEMBL18807990 | 0.80 | DPP7 (0.50) | EPHX2RRM1DPP7TLR2S1PR2 | |
| SCHEMBL19388210 | 0.79 | TLR2 (0.44) | EPHX2RRM1DPP7TLR2S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880829-A | ANALGESICS, HYPOTENSIVE AGENTS | G. D. SEARLE AND COMPANY (US) | 1989-11-14 | — | — | US | disclosed |
| US-4847241-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1989-07-11 | — | — | US | disclosed |
| US-4822775-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1989-04-18 | — | — | US | disclosed |