Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 2/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8390709 | 0.98 | ADRA1A (0.58) | ADRA1APRMT1EPHX2PLA2G2AMAPK1 | |
| SCHEMBL27765049 | 0.94 | ADRA1A (0.47) | ADRA1APRMT1EPHX2ECE1DPP7 | |
| SCHEMBL8389957 | 0.94 | ADRA1A (0.47) | ADRA1APRMT1EPHX2ECE1DPP7 | |
| Ethylenediamine SCHEMBL9537618 | 0.93 | ADRA1A (0.53) | ADRA1APRMT1EPHX2PLA2G2ADPP7 | |
| SCHEMBL29360302 | 0.86 | ECE1 (0.58) | PLA2G2AECE1 | |
| SCHEMBL7290638 | 0.86 | ECE1 (0.58) | PLA2G2AECE1 | |
| SCHEMBL7290633 | 0.86 | ECE1 (0.58) | PLA2G2AECE1 | |
| SCHEMBL15623812 | 0.86 | ALDH1A2 (0.54) | DPP7MAPK1 | |
| Trifluoroacetic Acid SCHEMBL28629834 | 0.84 | S1PR1 (0.44) | ADRA1APRMT1ECE1TLR2 | |
| SCHEMBL23071875 | 0.84 | ADRA1A (0.47) | ADRA1APRMT1EPHX2PLA2G2AECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910351-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-28 | — | — | EP | disclosed |
| WO-1997049387-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |