Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL10520700 | 0.89 | ALDH1A1 (0.53) | ALDH1A1MAPTNPC1HSD17B10GFER | |
| Fumaric Acid SCHEMBL10520711 | 0.89 | ALDH1A1 (0.53) | ALDH1A1MAPTNPC1HSD17B10GFER | |
| SCHEMBL10519613 | 0.77 | ALDH1A1 (0.59) | ALDH1A1MAPTNPC1HSD17B10GFER | |
| SCHEMBL10520440 | 0.76 | HTT (0.47) | ALDH1A1MAPTNPC1HSD17B10GFER | |
| SCHEMBL10518186 | 0.74 | ALDH1A1 (0.56) | ALDH1A1MAPTNPC1HSD17B10GFER | |
| SCHEMBL10621996 | 0.74 | ALDH1A1 (0.58) | ALDH1A1MAPTNPC1HSD17B10GFER | |
| SCHEMBL10525332 | 0.74 | CYP2D6 (0.34) | ALDH1A1HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL24170202 | 0.73 | ALDH1A1 (0.54) | ALDH1A1MAPTNPC1HSD17B10GFER | |
| SCHEMBL10519240 | 0.73 | ALDH1A1 (0.54) | ALDH1A1MAPTNPC1HSD17B10GFER | |
| SCHEMBL10161009 | 0.72 | GABRA5 (0.46) | ALDH1A1MAPTNPC1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183191-B1 | THIENYLTHIAZOLE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-10 | — | — | EP | claimed |
| US-4720493-A | Thienylthiazole compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-01-19 | — | — | US | claimed |
| EP-0183191-A1 | Thienylthiazole compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-06-04 | — | — | EP | claimed |
| EP-0183191-B1 | THIENYLTHIAZOLE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-10 | — | — | EP | disclosed |