Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 10/20 | 0.52 |
| ▸ | ACE | P12821 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086011 | 1.00 | FKBP1A (0.52) | FKBP1AACEMEN1KMT2AUSP2 | |
| SCHEMBL19955370 | 0.91 | FKBP1A (0.51) | FKBP1AACEMEN1KMT2AUSP2 | |
| SCHEMBL13609888 | 0.91 | FKBP1A (0.51) | FKBP1AACEMEN1KMT2AUSP2 | |
| SCHEMBL3268475 | 0.85 | FKBP1A (0.50) | FKBP1AACEMEN1KMT2AUSP2 | |
| SCHEMBL14370435 | 0.85 | ACE (0.54) | FKBP1AACEMEN1KMT2AUSP2 | |
| SCHEMBL9877388 | 0.84 | FKBP1A (0.49) | FKBP1AACEMEN1KMT2ATSHR | |
| SCHEMBL9878033 | 0.84 | FKBP1A (0.49) | FKBP1AACEMEN1KMT2ATSHR | |
| SCHEMBL9594309 | 0.83 | ACE (0.52) | FKBP1AACEMEN1KMT2AUSP2 | |
| SCHEMBL10959623 | 0.83 | ACE (0.52) | FKBP1AACEMEN1KMT2AUSP2 | |
| SCHEMBL4796474 | 0.83 | ACE (0.51) | FKBP1AACEMEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4818749-A | Carboxyalkyl dipeptides and medical use thereof in treating hypertension and congestive heart failure | SCHERING CORPORATION (US) | 1989-04-04 | — | — | US | disclosed |