Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10519602 | 0.89 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL10518331 | 0.89 | MAPT (0.62) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| Fumaric Acid SCHEMBL10520811 | 0.85 | MAPT (0.56) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| Maleic Acid SCHEMBL10520798 | 0.85 | MAPT (0.56) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL10519264 | 0.83 | KMT2A (0.57) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL10519297 | 0.82 | MEN1 (0.55) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL10519183 | 0.81 | MAPT (0.57) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL10520584 | 0.80 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL10518084 | 0.80 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL10521322 | 0.79 | MAPT (0.55) | ALDH1A1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183191-B1 | THIENYLTHIAZOLE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-10 | — | — | EP | disclosed |
| US-4720493-A | Thienylthiazole compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0183191-A1 | Thienylthiazole compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-06-04 | — | — | EP | disclosed |