Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10519264 | 0.88 | KMT2A (0.57) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10518366 | 0.87 | MAPT (0.53) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10519297 | 0.86 | MEN1 (0.55) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10518331 | 0.85 | MAPT (0.62) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10519488 | 0.83 | ALDH1A1 (0.52) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10519602 | 0.81 | ALDH1A1 (0.63) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| Maleic Acid SCHEMBL10520798 | 0.81 | MAPT (0.56) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| Fumaric Acid SCHEMBL10520811 | 0.81 | MAPT (0.56) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10520990 | 0.79 | ALDH1A1 (0.60) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| Oxalic Acid SCHEMBL10622034 | 0.77 | ALDH1A1 (0.46) | MAPTKDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183191-B1 | THIENYLTHIAZOLE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-10 | — | — | EP | disclosed |
| US-4720493-A | Thienylthiazole compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0183191-A1 | Thienylthiazole compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-06-04 | — | — | EP | disclosed |