Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10519297 | 0.90 | MEN1 (0.55) | KMT2AMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL10518331 | 0.89 | MAPT (0.62) | KMT2AMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL10521322 | 0.88 | MAPT (0.55) | KMT2AMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL10519488 | 0.87 | ALDH1A1 (0.52) | KMT2AMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL10518366 | 0.86 | MAPT (0.53) | KMT2AMAPTALDH1A1KDM4EMEN1 | |
| Maleic Acid SCHEMBL10520798 | 0.85 | MAPT (0.56) | KMT2AMAPTALDH1A1KDM4EMEN1 | |
| Fumaric Acid SCHEMBL10520811 | 0.85 | MAPT (0.56) | KMT2AMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL10519602 | 0.83 | ALDH1A1 (0.63) | KMT2AMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL10520990 | 0.83 | ALDH1A1 (0.60) | KMT2AMAPTALDH1A1KDM4EMEN1 | |
| Oxalic Acid SCHEMBL10622034 | 0.81 | ALDH1A1 (0.46) | KMT2AMAPTALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183191-B1 | THIENYLTHIAZOLE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-10 | — | — | EP | disclosed |
| US-4720493-A | Thienylthiazole compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0183191-A1 | Thienylthiazole compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-06-04 | — | — | EP | disclosed |