Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730157 | 0.76 | ALDH1A1 (0.38) | KMT2AMEN1CA1CA2CA5A | |
| SCHEMBL30980416 | 0.76 | ALDH1A1 (0.40) | KMT2AMEN1CA1CA2CA5A | |
| SCHEMBL9223324 | 0.76 | ALDH1A1 (0.40) | KMT2AMEN1CA1CA2CA5A | |
| SCHEMBL10524410 | 0.73 | KMT2A (0.39) | KMT2AMEN1CA1CA2CA5A | |
| SCHEMBL9586437 | 0.73 | ALDH1A1 (0.38) | KMT2AMEN1CA1CA2CA5A | |
| SCHEMBL9730399 | 0.73 | CA1 (0.45) | KMT2AMEN1CA1CA2CA5A | |
| SCHEMBL9730664 | 0.72 | KMT2A (0.37) | KMT2AMEN1CA1CA2CA5A | |
| SCHEMBL9852636 | 0.71 | MAPT (0.42) | KMT2AMEN1CA1CA2CA5A | |
| SCHEMBL8159483 | 0.71 | MAPT (0.44) | KMT2AMEN1CA1CA2CA5A | |
| SCHEMBL1765911 | 0.70 | MAPT (0.47) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343462-A1 | Aminoguanidino azines | BAYER AG (DE) | 1989-11-29 | — | — | EP | disclosed |