Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29372079 | 0.84 | ABCB11 (0.49) | MAPTKMT2AMEN1ALOX15HSD17B10 | |
| SCHEMBL9713437 | 0.83 | PDE7A (0.40) | MAPTKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL10502745 | 0.81 | L3MBTL1 (0.46) | MAPTENPP2KMT2AMEN1CYP3A4 | |
| SCHEMBL9643565 | 0.80 | ABCB11 (0.67) | MAPTKMT2AMEN1CYP3A4TSHR | |
| SCHEMBL9643247 | 0.78 | ABCB11 (0.47) | MAPTKMT2AMEN1ALOX15ABCB11 | |
| SCHEMBL10502679 | 0.77 | ABCB11 (0.46) | MAPTKMT2AMEN1ALOX12ABCB11 | |
| SCHEMBL10522283 | 0.76 | ABCB11 (0.42) | MAPTKMT2AMEN1HSD17B10ABCB11 | |
| SCHEMBL10522294 | 0.76 | ABCB11 (0.42) | MAPTKMT2AMEN1HSD17B10ABCB11 | |
| SCHEMBL9643206 | 0.75 | ABCB11 (0.44) | MAPTKMT2AMEN1ALOX15HSD17B10 | |
| SCHEMBL29371517 | 0.74 | KMT2A (0.50) | MAPTKMT2AMEN1ABCB11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0146145-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1989-08-30 | — | — | EP | disclosed |
| US-4593120-A | Naphthalene-1,4-dicarboxylic acid group | SYNTEX (U.S.A.) INC. (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0146145-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-06-26 | — | — | EP | disclosed |