Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2033421 | 0.87 | L3MBTL1 (0.64) | L3MBTL1HRH4KMT2ALMNATP53 | |
| SCHEMBL3881407 | 0.86 | L3MBTL1 (0.55) | L3MBTL1HRH4KMT2ALMNATP53 | |
| SCHEMBL2378330 | 0.86 | L3MBTL1 (0.55) | L3MBTL1HRH4KMT2ALMNATP53 | |
| SCHEMBL10520056 | 0.83 | HSD11B1 (0.46) | HRH4KMT2AALDH1A1CA12CA1 | |
| SCHEMBL519919 | 0.82 | ALDH1A1 (0.53) | L3MBTL1HRH4KMT2ALMNAPOLB | |
| SCHEMBL10722273 | 0.81 | L3MBTL1 (0.74) | L3MBTL1KMT2ALMNATP53ALOX15 | |
| SCHEMBL10578175 | 0.81 | SMN1; SMN2 (0.55) | KMT2ATP53TSHRALDH1A1HPGD | |
| SCHEMBL9539394 | 0.81 | RXFP1 (0.58) | HRH4CA12CA1CA2CA7 | |
| SCHEMBL31172456 | 0.81 | SMN1; SMN2 (0.55) | KMT2ATP53TSHRALDH1A1HPGD | |
| SCHEMBL10518702 | 0.81 | HSD17B10 (0.53) | KMT2ALMNAALOX15TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300366-A1 | Non-fugitive aromatic diamine catalytic chain extenders | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1989-01-25 | — | — | EP | claimed |