Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | RARB | P10826 | 4/20 | 0.54 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29612130 | 0.95 | NR5A1 (0.56) | NR5A1SLC2A1TP53TSHRLTA4H | |
| SCHEMBL29611696 | 0.95 | NR5A1 (0.56) | NR5A1SLC2A1TP53TSHRLTA4H | |
| SCHEMBL10415894 | 0.94 | PTGES (0.54) | CYP2D6CYP3A4CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL20357879 | 0.91 | CYP2D6 (0.56) | CYP2D6CYP3A4CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL29611836 | 0.91 | NR5A1 (0.61) | RARBNR5A1SLC2A1TP53TSHR | |
| SCHEMBL29611828 | 0.91 | NR5A1 (0.61) | RARBNR5A1SLC2A1TP53TSHR | |
| SCHEMBL9752262 | 0.90 | RARB (0.55) | CYP2D6CYP3A4CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL10399310 | 0.90 | ALDH1A1 (0.56) | CYP2D6CYP3A4CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL29611988 | 0.87 | NR5A1 (0.52) | RARBNR5A1SLC2A1TP53TSHR | |
| SCHEMBL10525466 | 0.87 | NR5A1 (0.72) | RARBNR5A1SLC2A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1113329-A | — | — | None | — | — | JP | disclosed |
| JP-H01113329-A | OPTICALLY ACTIVE BIPHENYL ETHER COMPOUND | ADEKA ARGUS CHEM CO LTD | 1989-05-02 | — | — | JP | disclosed |