Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tributylmethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 7/20 | 0.39 |
| ▸ | PPARD | Q03181 | 7/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tributylmethylammonium SCHEMBL4357067 | 0.92 | SLC22A1 (0.43) | ALOX15BBOX1SLC22A1DNM1AKR1B1 | |
| Oxalic Acid SCHEMBL7624957 | 0.90 | DNM1 (0.50) | ALOX15SLC22A1DNM1GPR84PPARG | |
| Tributylmethylammonium SCHEMBL1052295 | 0.88 | BBOX1 (0.47) | ALOX15BBOX1SLC22A1DNM1AKR1B1 | |
| Oxalic Acid SCHEMBL29167020 | 0.88 | DNM1 (0.52) | SLC22A1DNM1GPR84PPARGPPARD | |
| Tributylmethylammonium SCHEMBL7580402 | 0.87 | BBOX1 (0.50) | BBOX1SLC22A1DNM1AKR1B1GPR84 | |
| Oxalic Acid SCHEMBL29166912 | 0.86 | DNM1 (0.50) | SLC22A1DNM1GPR84TSHRALDH1A1 | |
| Tributylmethylammonium SCHEMBL4357063 | 0.84 | BBOX1 (0.52) | BBOX1SLC22A1DNM1 | |
| Oxalic Acid SCHEMBL1050655 | 0.83 | ALOX15 (0.37) | ALOX15BBOX1SLC22A1DNM1AKR1B1 | |
| Tributylmethylammonium SCHEMBL4951132 | 0.83 | HCAR2 (0.48) | BBOX1TSHRTDP1 | |
| Tributylmethylammonium SCHEMBL5571632 | 0.83 | AKR1B1 (0.58) | ALOX15AKR1B1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7867471-B2 | Process for preparing advanced ceramic powders using onium dicarboxylates | SACHEM, INC. (US) | 2011-01-11 | — | — | US | disclosed |
| US-20090250850-A1 | PROCESS FOR PREPARING ADVANCED CERAMIC POWDERS USING ONIUM DICARBOXYLATES | SACHEM, INC. | 2009-10-08 | — | — | US | disclosed |