Pyruvate

Pyruvate

SCHEMBL1052425

CC(=O)C(=O)O.CCC(N)(N)C(=O)O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.40
CYP1A2 P05177 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 2/20 0.40
THRB P10828 1/20 0.40
GRM2 Q14416 1/20 0.35
GRM3 Q14832 1/20 0.35
ARG1 P05089 1/20 0.34
ARG2 P78540 1/20 0.34
GGT1 P19440 1/20 0.31
FFAR3 O14843 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL6374415 0.90 ALDH1A1 (0.43) MEN1CYP1A2KMT2AALDH1A1THRB
SCHEMBL7567590 0.89 MEN1 (0.46) MEN1CYP1A2KMT2AALDH1A1THRB
SCHEMBL18370 0.89
Hydrochloric Acid SCHEMBL6948114 0.87
Hydrochloric Acid SCHEMBL6620873 0.87 MEN1 (0.44) MEN1CYP1A2KMT2AALDH1A1THRB
Bromide SCHEMBL6844526 0.87
Ethylene Glycol SCHEMBL28284886 0.82 MEN1 (0.41) MEN1CYP1A2KMT2AALDH1A1THRB
Trifluoroacetic Acid SCHEMBL29002241 0.76 MEN1 (0.38) MEN1CYP1A2KMT2AALDH1A1THRB
Acetic Acid SCHEMBL28820430 0.72 FFAR3 (0.37) MEN1CYP1A2KMT2AALDH1A1THRB
Pyruvate SCHEMBL21145119 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7863032-B2 Bacillus licheniformis chromosome-encoded endoglucanase NOVOZYMES, INC. (US) 2011-01-04 US disclosed
US-20090275104-A1 Bacillus licheniformis chromosone NOVOZYMES A/S (DK) 2009-11-05 US disclosed
US-7494798-B2 Bacillus licheniformis chromosome NOVOZYMES, INC. (US) 2009-02-24 US disclosed
US-20080050774-A1 Computer-based system for monitoring differential expression; host cells NOVOZYMES A/S (DK) 2008-02-28 US disclosed