Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567590 | 0.97 | MEN1 (0.46) | — | |
| SCHEMBL18370 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL6948114 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL6620873 | 0.94 | MEN1 (0.44) | — | |
| Acetic Acid SCHEMBL6374415 | 0.92 | ALDH1A1 (0.43) | — | |
| Ethylene Glycol SCHEMBL28284886 | 0.89 | MEN1 (0.41) | — | |
| Pyruvate SCHEMBL1052425 | 0.87 | MEN1 (0.40) | — | |
| Trifluoroacetic Acid SCHEMBL29002241 | 0.83 | MEN1 (0.38) | — | |
| Alpha-Ketoglutaric Acid SCHEMBL638179 | 0.78 | EGLN1 (0.56) | — | |
| Valine SCHEMBL8574768 | 0.78 | SLC7A5 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040005708-A1 | Polypeptide derivatives and nucleic acid carriers containing the same | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2004-01-08 | — | — | US | disclosed |
| EP-1285942-A1 | POLYPEPTIDE DERIVATIVES AND NUCLEIC ACID CARRIERS CONTAINING THE SAME | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2003-02-26 | — | — | EP | disclosed |