SCHEMBL7567590

SCHEMBL7567590

CCC(N)(N)C(=O)O.CCC(N)(N)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
CYP1A2 P05177 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 2/20 0.46
THRB P10828 1/20 0.46
GRM2 Q14416 2/20 0.40
GRM3 Q14832 1/20 0.40
ARG1 P05089 2/20 0.39
ARG2 P78540 2/20 0.39
FFAR3 O14843 2/20 0.37
GGT1 P19440 1/20 0.36
TSHR P16473 2/20 0.35
HIF1A Q16665 2/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18370 1.00
Bromide SCHEMBL6844526 0.97
Hydrochloric Acid SCHEMBL6948114 0.97
Hydrochloric Acid SCHEMBL6620873 0.97 MEN1 (0.44) MEN1CYP1A2KMT2AALDH1A1THRB
Acetic Acid SCHEMBL6374415 0.94 ALDH1A1 (0.43) MEN1CYP1A2KMT2AALDH1A1THRB
Ethylene Glycol SCHEMBL28284886 0.92 MEN1 (0.41) MEN1CYP1A2KMT2AALDH1A1THRB
Pyruvate SCHEMBL1052425 0.89 MEN1 (0.40) MEN1CYP1A2KMT2AALDH1A1THRB
Trifluoroacetic Acid SCHEMBL29002241 0.85 MEN1 (0.38) MEN1CYP1A2KMT2AALDH1A1THRB
Alpha-Ketoglutaric Acid SCHEMBL638179 0.80 EGLN1 (0.56) MEN1CYP1A2KMT2AALDH1A1THRB
Valine SCHEMBL8574768 0.80 SLC7A5 (0.60) MEN1CYP1A2KMT2AALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1229124-A1 NUCLEIC ACID TRANSPORTER CONTAINING POLYPEPTIDE AND RECOMBINANT VIRUS VECTOR HISAMITSU PHARMACEUTICAL CO. INC. (JP) 2002-08-07 EP disclosed