Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 3/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | FDPS | P14324 | 6/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | BCL9 | O00512 | 3/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sempervirol SCHEMBL10524413 | 1.00 | KARS1 (0.66) | KARS1CYP19A1USP2CYP3A4MAPT | |
| Sempervirol SCHEMBL29495146 | 1.00 | KARS1 (0.66) | KARS1CYP19A1USP2CYP3A4MAPT | |
| Ferruginol SCHEMBL5315022 | 0.95 | KARS1 (0.73) | KARS1CYP19A1USP2CYP3A4MAPT | |
| Ferruginol SCHEMBL13423521 | 0.95 | KARS1 (0.73) | KARS1CYP19A1USP2CYP3A4MAPT | |
| Ferruginol SCHEMBL155580 | 0.95 | KARS1 (0.73) | KARS1CYP19A1USP2CYP3A4MAPT | |
| SCHEMBL18290298 | 0.83 | KARS1 (0.58) | KARS1CYP19A1USP2CYP3A4MAPT | |
| SCHEMBL17861419 | 0.82 | POLA1 (0.49) | KARS1CYP19A1USP2CYP3A4MAPT | |
| 18-Hydroxyferruginol SCHEMBL18290210 | 0.81 | KARS1 (0.67) | KARS1USP2CYP3A4MAPTMEN1 | |
| 18-Hydroxyferruginol SCHEMBL32666150 | 0.81 | KARS1 (0.67) | KARS1USP2CYP3A4MAPTMEN1 | |
| SCHEMBL21444399 | 0.80 | KARS1 (0.57) | KARS1CYP19A1USP2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1311020-A | — | — | None | — | — | JP | disclosed |
| WO-2016097759-A1 | ANTHELMINTIC COMPOUNDS | ABERYSTWYTH UNIVERSITY (GB) | 2016-06-23 | — | — | WO | disclosed |
| JP-H01311020-A | ANTIBACTERIAL AGENT, EXTERNAL PREPARATION OF SKIN AND COMPOSITION FOR ORAL CAVITY USING THE SAME AGENT | SHISEIDO CO LTD | 1989-12-15 | — | — | JP | disclosed |