Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GNPAT | O15228 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | CPA2 | P48052 | 1/20 | 0.35 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | NMT2 | O60551 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10524634 | 1.00 | SIRT6 (0.43) | SIRT6SIRT1CA1CA2OPRM1 | |
| SCHEMBL30595069 | 0.91 | SIRT6 (0.41) | SIRT6SIRT1CA1CA2SLC15A2 | |
| SCHEMBL26446682 | 0.89 | SLC15A2 (0.48) | SIRT6SIRT1CA1CA2SLC15A2 | |
| SCHEMBL30493605 | 0.89 | OPRM1 (0.41) | CA1CA2OPRM1GRIA1GNPAT | |
| SCHEMBL29396819 | 0.88 | SLC15A2 (0.50) | SIRT6SIRT1CA1CA2SLC15A2 | |
| SCHEMBL7160634 | 0.87 | MMP2 (0.37) | SLC15A2 | |
| SCHEMBL7160638 | 0.87 | MMP2 (0.37) | SLC15A2 | |
| SCHEMBL29397843 | 0.87 | SLC15A2 (0.46) | SIRT6SIRT1CA1CA2SLC15A2 | |
| SCHEMBL29396585 | 0.87 | SLC15A2 (0.46) | SIRT6SIRT1CA1CA2SLC15A2 | |
| SCHEMBL10525648 | 0.84 | CD40 (0.33) | SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4866121-A | B cell differentiating peptides and conjugates thereof | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-09-12 | — | — | US | disclosed |
| US-4783442-A | B-cell differentiating peptides | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-11-08 | — | — | US | disclosed |