Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 9/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10527375 | 0.89 | KAT2B (0.37) | KAT2BBRD4CREBBPTNKSTNKS2 | |
| SCHEMBL10526697 | 0.88 | IDO1 (0.37) | KAT2BBRD4CREBBPTNKSTNKS2 | |
| SCHEMBL10526729 | 0.87 | IDO1 (0.36) | KAT2BBRD4CREBBP | |
| SCHEMBL10527283 | 0.86 | BRD4 (0.39) | KAT2BBRD4CREBBP | |
| SCHEMBL10527272 | 0.86 | TNKS (0.36) | KAT2BBRD4CREBBPTNKSTNKS2 | |
| SCHEMBL10526781 | 0.85 | LATS1 (0.37) | KAT2BBRD4CREBBP | |
| SCHEMBL10924720 | 0.85 | ALDH1A1 (0.35) | BRD4CREBBP | |
| SCHEMBL10525166 | 0.84 | CCNB2 (0.37) | KAT2BTNKSTNKS2GSK3BCCNB2 | |
| SCHEMBL10524485 | 0.83 | TLR8 (0.45) | KAT2BGSK3B | |
| SCHEMBL10527803 | 0.82 | DHFR (0.35) | KAT2BBRD4TNKSTNKS2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4801590-A | ANGINA, ANTICANCER, CARDIOVASCULAR DISORDERS, HEADACHES, PSORIASIS, ASTHMA, ANTICOAGULANTS | BEIERSDORF AG (DE) | 1989-01-31 | — | — | US | claimed |
| US-4801590-A | ANGINA, ANTICANCER, CARDIOVASCULAR DISORDERS, HEADACHES, PSORIASIS, ASTHMA, ANTICOAGULANTS | BEIERSDORF AG (DE) | 1989-01-31 | — | — | US | disclosed |
| EP-0253171-A1 | Pyrido[1,8]naphthyridinones, process for their preparation and their use and compositions containing them | Beiersdorf-Lilly GmbH (DE) | 1988-01-20 | — | — | EP | disclosed |