Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11269182 | 0.76 | SOS2 (0.39) | PPARGPPARAKDM4ENPC1RAB9A | |
| SCHEMBL10524862 | 0.74 | CFD (0.41) | KDM4EAKT1HTTRAB9AHSD17B10 | |
| SCHEMBL3174222 | 0.71 | MAPT (0.55) | KDM4ECYP3A4ALOX12TDP1SLC22A6 | |
| Hydrochloric Acid SCHEMBL11272178 | 0.69 | CDYL (0.40) | PPARGPPARAKDM4ETDP1TYMS | |
| SCHEMBL18499932 | 0.69 | ALDH1A1 (0.58) | KDM4ECYP3A4SLC22A6HTTNPC1 | |
| SCHEMBL30002719 | 0.68 | HTT (0.61) | KDM4ECYP3A4ALOX12TDP1SLC22A6 | |
| SCHEMBL6688920 | 0.68 | HTT (0.56) | KDM4ECYP3A4ALOX12TDP1SLC22A6 | |
| SCHEMBL4444465 | 0.68 | HTT (0.61) | KDM4ECYP3A4ALOX12TDP1SLC22A6 | |
| SCHEMBL926733 | 0.67 | SLC22A6 (0.42) | KDM4ECYP3A4ALOX12TDP1TYMS | |
| SCHEMBL7638665 | 0.67 | KDM4E (0.46) | KDM4ECYP3A4ALOX12TDP1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4840965-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1989-06-20 | — | — | US | disclosed |