Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.73 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.73 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.70 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.70 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.70 |
| ▸ | FABP4 | P15090 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.64 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | DHFR | P00374 | 1/20 | 0.64 |
| ▸ | MPO | P05164 | 1/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25449209 | 0.92 | AKR1C3 (0.66) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C1 | |
| SCHEMBL30320327 | 0.89 | FABP4 (0.80) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C1 | |
| SCHEMBL355549 | 0.89 | FABP4 (0.80) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C1 | |
| SCHEMBL9691899 | 0.87 | FABP4 (0.77) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C1 | |
| SCHEMBL6142375 | 0.87 | FABP4 (0.84) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C1 | |
| SCHEMBL16127718 | 0.85 | CA12 (0.60) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C1 | |
| SCHEMBL848485 | 0.84 | MAPT (0.68) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C1 | |
| SCHEMBL30567367 | 0.84 | MAPT (0.68) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C1 | |
| SCHEMBL10935816 | 0.82 | AKR1C3 (0.57) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C1 | |
| SCHEMBL1186480 | 0.82 | AKR1C3 (0.77) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098098-B1 | ACRIDINECARBOXAMIDE COMPOUNDS | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1989-02-08 | — | — | EP | disclosed |
| US-4590277-A | BACTERICIDES, ANTITUMOR AGENTS | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1986-05-20 | — | — | US | disclosed |
| EP-0098098-A2 | Acridinecarboxamide compounds | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1984-01-11 | — | — | EP | disclosed |