SCHEMBL30567367

SCHEMBL30567367

CC(=O)c1ccccc1Nc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.68
ALOX15 P16050 1/20 0.68
MEN1 O00255 1/20 0.68
KMT2A Q03164 1/20 0.68
FABP4 P15090 1/20 0.67
AKR1C3 P42330 4/20 0.60
AKR1C2 P52895 4/20 0.60
SIRT2 Q8IXJ6 8/20 0.56
PTGS1 P23219 1/20 0.51
AKR1B10 O60218 1/20 0.51
AKR1B1 P15121 1/20 0.51
AKR1C4 P17516 1/20 0.51
AKR1C1 Q04828 1/20 0.51
RXFP1 Q9HBX9 1/20 0.51
MT-CO2 P00403 1/20 0.50
SIRT1 Q96EB6 1/20 0.50
POLB P06746 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL848485 1.00 MAPT (0.68) MAPTALOX15MEN1KMT2AFABP4
Acetonitrile SCHEMBL27301956 0.91 MEN1 (0.59) MAPTALOX15MEN1KMT2AFABP4
SCHEMBL25449209 0.87 AKR1C3 (0.66) MAPTALOX15MEN1KMT2AFABP4
SCHEMBL8052123 0.87 MEN1 (0.58) MAPTALOX15MEN1KMT2AFABP4
SCHEMBL10936401 0.87 MEN1 (0.58) MAPTALOX15MEN1KMT2AFABP4
Fenamic Acid SCHEMBL27925717 0.86 FABP4 (0.82) MAPTALOX15MEN1KMT2AFABP4
SCHEMBL30567365 0.85 MEN1 (0.56) MAPTALOX15MEN1KMT2AFABP4
SCHEMBL7844252 0.85 MEN1 (0.56) MAPTALOX15MEN1KMT2AFABP4
SCHEMBL6620978 0.85 AKR1C3 (0.57) MAPTALOX15MEN1KMT2AFABP4
SCHEMBL30982117 0.85 AKR1C3 (0.57) MAPTALOX15MEN1KMT2AFABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115947690-B Preparation method of indazole molecular building block and application of indazole molecular building block in drug synthesis 安徽医科大学 2025-04-08 CN disclosed
CN-116589406-A Preparation method of polysubstituted acridine derivative 深圳职业技术学院 2023-08-15 CN disclosed