Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 5/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.33 |
| ▸ | CDK1 | P06493 | 3/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10526786 | 0.91 | UTS2R (0.41) | UTS2RIDO1KAT2BELANETLR8 | |
| SCHEMBL10527105 | 0.89 | TLR8 (0.46) | UTS2RKAT2BELANETLR8TLR7 | |
| SCHEMBL10527877 | 0.86 | KAT2B (0.37) | KAT2BCRBNDDB1CCNB2CDK1 | |
| SCHEMBL10526370 | 0.84 | IDO1 (0.39) | IDO1KAT2BCRBNDDB1CCNB2 | |
| SCHEMBL10526729 | 0.79 | IDO1 (0.36) | UTS2RIDO1KAT2BCRBNDDB1 | |
| SCHEMBL10526800 | 0.79 | ALDH1A1 (0.37) | CRBNDDB1CCNB2CDK1CCNB1 | |
| SCHEMBL10526975 | 0.78 | CCNB2 (0.42) | CRBNDDB1CCNB2CDK1CCNB1 | |
| SCHEMBL10527413 | 0.77 | CCNB2 (0.37) | CRBNDDB1CCNB2CDK1CCNB1 | |
| SCHEMBL10527139 | 0.77 | CRBN (0.37) | CRBNDDB1CCNB2CDK1CCNB1 | |
| SCHEMBL10526790 | 0.76 | KAT2B (0.35) | UTS2RIDO1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4801590-A | ANGINA, ANTICANCER, CARDIOVASCULAR DISORDERS, HEADACHES, PSORIASIS, ASTHMA, ANTICOAGULANTS | BEIERSDORF AG (DE) | 1989-01-31 | — | — | US | disclosed |
| EP-0253171-A1 | Pyrido[1,8]naphthyridinones, process for their preparation and their use and compositions containing them | Beiersdorf-Lilly GmbH (DE) | 1988-01-20 | — | — | EP | disclosed |