Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046208 | 0.89 | ALDH1A1 (0.47) | TBXA2RGAAALDH1A1MAPTKMT2A | |
| SCHEMBL9046179 | 0.79 | MAPT (0.50) | GAAALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL10921909 | 0.77 | TBXA2R (0.53) | TBXA2R | |
| SCHEMBL9045008 | 0.75 | DRD2 (0.43) | GAAALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL14997683 | 0.71 | ALDH1A1 (0.55) | TBXA2RGAAALDH1A1MAPTKMT2A | |
| SCHEMBL30572069 | 0.71 | TTR (0.47) | GAAKMT2ALMNAMEN1SRD5A2 | |
| SCHEMBL26119256 | 0.71 | TTR (0.47) | GAAKMT2ALMNAMEN1SRD5A2 | |
| SCHEMBL9375392 | 0.69 | TBXA2R (0.56) | TBXA2RGAAALDH1A1MAPTKMT2A | |
| SCHEMBL9371402 | 0.69 | TBXA2R (1.00) | TBXA2R | |
| SCHEMBL11463305 | 0.69 | HSD17B3 (0.48) | GAAALDH1A1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882351-A | CARDIOVASCULAR DISORDERS; | ROUSSEL UCLAF (FR) | 1989-11-21 | — | — | US | disclosed |