Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX2 | Q96LB1 | 4/20 | 0.82 |
| ▸ | OPRM1 | P35372 | 14/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 13/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.61 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154048 | 0.90 | MRGPRX2 (1.00) | MRGPRX2OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL29449917 | 0.90 | MRGPRX2 (1.00) | MRGPRX2OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL29583693 | 0.90 | MRGPRX2 (1.00) | MRGPRX2OPRM1OPRD1OPRK1SLC22A1 | |
| Hydrochloric Acid SCHEMBL27754570 | 0.90 | MRGPRX2 (0.98) | MRGPRX2OPRM1OPRD1OPRK1SLC22A1 | |
| Methoxymethane SCHEMBL27466715 | 0.88 | MRGPRX2 (0.94) | MRGPRX2OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL28654569 | 0.87 | MRGPRX2 (0.77) | MRGPRX2OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL8362208 | 0.86 | MRGPRX2 (0.81) | MRGPRX2OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL7668849 | 0.85 | MRGPRX2 (0.74) | MRGPRX2OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL8356924 | 0.84 | MRGPRX2 (0.79) | MRGPRX2OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL28654572 | 0.83 | MRGPRX2 (0.70) | MRGPRX2OPRM1OPRD1OPRK1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1149788-A | — | — | None | — | — | JP | disclosed |
| JP-H01149788-A | NOVEL MORPHINE DERIVATIVE | CHUGAI PHARMACEUT CO LTD | 1989-06-12 | — | — | JP | disclosed |